First atomic structures of Tau filaments from Alzheimer’s disease brain

MRC Laboratory of Molecular Biology| Thu Jul 06 01:48:12 EDT 2017
First atomic structures of Tau filaments from Alzheimer’s disease brain
Tau filament structures, rendered in blue and white. In the background, a photomicrograph of a Bodian silver-stain preparation shows a neuron from the cerebral cortex of an individual affected by Alzheimer disease. The cytoplasm around the nucleus contains a flame-shaped neurofibrillary tangle. The Tau filaments appear to wrap around the neuron.

Alzheimer’s disease, the most common neurodegenerative disease, is characterised by the formation of filamentous Tau protein inside nerve cells and a....

Read at Source
Related News