Insights Into Key Molecular Process Underlying Many Cancers

Northwestern Medicine
Ali Shilatifard, PhD, Robert Francis Furchgott Professor and chair of Biochemistry and Molecular Genetics, was the principal investigator of the study. A Northwestern Medicine study provides new insight into a protein complex called COMPASS (Complex of Proteins Associated with Set1) and its function during histone methylation — a key modification that regulates gene expression. The findings, published in Molecular Cell, could lead to